ATF4 helps mitochondria pass the stress test
نویسنده
چکیده
The transcription factor ATF4 coordinates the mitochondrial stress response in mammalian cells.
منابع مشابه
Effects of ATF4 on PGC1α expression in brown adipose tissue and metabolic responses to cold stress.
OBJECTIVE We have shown previously that the expression of peroxisome proliferator activated receptor gamma coactivator (PGC1α) increases significantly in the white and brown adipose tissue of activating transcription factor 4 (ATF4) global knockout mice, which suggests that ATF4 is involved in the regulation of PGC1α expression. The goal of the current study is to investigate this possibility a...
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عنوان ژورنال:
دوره 216 شماره
صفحات -
تاریخ انتشار 2017